Trymethylamine-N-oxide, a gut-derived metabolite, induces myofibroblastic activation of valvular interstitial cells through endoplasmic reticulum stress

Sudi S, Suresh DS, Kolli, T, Mancera Azamar KM, Dickson A, Mohammadalizadeh Z, Porras AM (2026) Scientific Reports

Developing a cell culture protocol to induce quiescence in intestinal fibroblasts using design of experiments statistical optimization

Mohammadalizadeh Z, Bauer Estrada K, Almonte M, Fogg K, Porras AM (2025) Research Square [Preprint]

Engineered in vitro models to improve the mechanistic understanding and treatment of neglected tropical diseases caused by protozoan parasites

Monjute TG, Rosero JG, Ruley JAU, Hernandez AJU, Kime PE, Porras AM (2024) GEN Biotechnology

Engineering the aortic valve extracellular matrix through stages of development, aging, and disease

Scott AJ, Simon LR, Hutson HN, Porras AM, Masters KS (2021) Journal of Molecular and Cellular Cardiology

Creation of disease-inspired biomaterial environments to mimic pathological events in early calcific aortic valve disease

Porras AM, Westlund JA, Evans AD, Masters KS (2018) Proceedings of the National Academy of Sciences of the United States of America

Robust generation of quiescent porcine valvular interstitial cell cultures

Porras AM, Engeland N, Marchbanks E, McCormack A, Bouten C, Yacoub MH, Latif N, Masters KS (2017) JAHA: Journal of the American Heart Association

Engineering approaches to study fibrosis in 3-D in vitro systems

Porras AM, Hutson HN, Berger AJ, Masters KS (2016) Current Opinions in Biotechnology