Trymethylamine-N-oxide, a gut-derived metabolite, induces myofibroblastic activation of valvular interstitial cells through endoplasmic reticulum stress

Sudi S, Suresh DS, Kolli, T, Mancera Azamar KM, Dickson A, Mohammadalizadeh Z, Porras AM (2026) Scientific Reports

Engineering the aortic valve extracellular matrix through stages of development, aging, and disease

Scott AJ, Simon LR, Hutson HN, Porras AM, Masters KS (2021) Journal of Molecular and Cellular Cardiology

Creation of disease-inspired biomaterial environments to mimic pathological events in early calcific aortic valve disease

Porras AM, Westlund JA, Evans AD, Masters KS (2018) Proceedings of the National Academy of Sciences of the United States of America

Robust generation of quiescent porcine valvular interstitial cell cultures

Porras AM, Engeland N, Marchbanks E, McCormack A, Bouten C, Yacoub MH, Latif N, Masters KS (2017) JAHA: Journal of the American Heart Association

Calcific aortic valve disease: A battle of the sexes

Porras AM, McCoy CM, Masters KS (2017) Circulation Research

Development of aortic valve disease in familial hypercholesterolemic swine: Implications for elucidating disease etiology

Porras AM, Shanmuganayagam D, Meudt JJ, Kreuger CG, Rahko PS, Reed JD, Masters KS (2015) JAHA: Journal of the American Heart Association

Wave mice: A new tool in the quest to characterize aortic valvular disease etiologies

Porras AM, Masters KS (2015) Journal of Thoracic Disease

Gene expression profiling of valvular interstitial cells in Rapacz familial hypercholesterolemic swine

Porras AM, Shanmuganayagam D, Meudt JJ, Krueger CG, Reed JD, Masters KS (2014) Genomics Data

Manipulation of valve composition to elucidate the role of collagen in aortic valve calcification

Rodriguez KJ, Piechura LM, Porras AM, Masters KS (2014) BMC Cardiovascular Disorders